Mechanism of Tissue Injury in Type III
Ubegins when
Ag/Ab immune complexes are deposited onto tissue
Ucomplement is
activated releasing anaphylotoxins (C3a & C5a)
Uanaphylotoxins
stimulate mast cells and basophils to release chemotactic factors & amines
(histamine)
Ueffector
cells are called into area which release their lysosomal enzymes
Ua local
inflammatory reaction occurs
