Genetic
Factors
Uno direct
evidence in humans
Uthose that
inherit certain MHC alleles have higher probability of developing diseases
HLA allele
Disease
Relative
risk
NOTE: Relative risk is the Atimes
higher@ the risk compared to normal population
DR4
B27
DR2
DR3
DR3/DQW8
pemphigus
vulgaris -
blistering skin
disorder
5
Ankylosing
spondylitis
90
Goodpasture=s syndrome
16
Myasthenia
gravis
10
Diabetes
mellitus
100
