Environmental Factors
•
U
some factors that may cause alterations in self- antigen
•
e
Drugs
•
e
Toxins
•
Ë
Penicillin - autoimmune Hemolytic anemia
•
Ë
Procainamide - SLE
•
Ë
Mercuric chloride - antinuclear antibodies
•
Ë
Polyvinyl chloride - scleroderma
•
Ë
Silicon - scleroderma & Rheumatoid arthritis
•
e
Ultraviolet radiation
•
Ë
correlated to increased risk for skin cancers but
not with autoimmune disorders