Detection
of Immune Response - 3
Detection of Infections: continued
ediagnosis of immunity (past infection)
-antigen-specific
IgG is detectable within 1 - 2 weeks after primary infection
-antigen-specific
IgG levels peak at 4 - 8 weeks and then declines.
It remains at detectable levels the rest of the patients life.
-immunity to a
specific antigen can be conferred through immunizations
-re-infection
produces low titer IgM and a higher titer IgG
-congenital
infection has detectable IgM or IgA in fetal, cord, or newborn blood. Detectable IgG in these specimens is of maternal origin.
