Testing Panel – Immune Competence
- 2
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U
Non-specific tests that evaluate immune response:
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U
Specific tests that evaluate immune response:
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e
Tests for Humoral immune response:
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serum immunoglobulin levels (IgG, IgM, & IgA)
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e
Tests for Cell-mediated immune response:
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number and type of leukocytes (WBC differential)
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skin test (lymphocyte response)
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Parameter measured
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Function measured
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Total T cells
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Subsets of T cells
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Total B cells
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Immunoglobulins
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NK cells
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Monocytes/Macrophages
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Complement components
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Activation of T lymphs with mitogens
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T cell ratios
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Activation of B lymphs with mitogens
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B lymphs
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Antibody-dependent cell-mediated cytotoxicity (ADCC)
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Phagocytic & antigen-presenting
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Opsonization, humoral defense & Ab-mediated cell lysis