Immunotyping in Leukemia & Lymphoma
eB cell-associated antigens:
_sIg
sIg = surface immunoglobulin
_CD10 or
CD = cluster of differentiation
CALLA
CALLA = common acute lymphoblastic leukemia
associated
on normal
immature & ALL B cells
not on mature
circulating B cells
eT cell-associated antigens:
_CD3
_CD4
_CD8
_CD9
on T cells and T
cell neoplasms
on THelper cells, macrophages, and T cell neoplasms
on TCytotoxic cells and subsets of NK cells
on cells of ALL
(immature T cells)
eMiscellaneous marker:
_TdT
TdT = Terminal deoxyribonucleotidyl transferase
on cells of ALL
and lymphomas (immature B cells)
on mature B cells
not on plasma cells