Valence
of Ag & Conc. Of Ab-Ag
Valence of Antigen:
eit is the of
identical epitopes contained on an antigen
Umultivalent (>1 identical epitope) antigens bind
much stronger
with antibodies than do univalent antigens
Uthe size of
Ag-Ab complexes is largely dependent on the valence of antigens
Concentration of Antigens & Antibodies:
ethe number of
antigen-binding sites (thus ab=s)
and the number
of epitopes (thus antigens) influences the formation of Ag-Ab complexes.
Uzone of
equivalence:
the
concentration of antigen and antibody are such
that maximum
Ag-Ab complexes are formed
