Manifestations of Ab-Ag Reactions
•ePrimary manifestation:
•eSecondary manifestation:
•Ubonds form between the idiotype and epitope
•Ureaction only detected if a label has been attached to one of the reactants
•UAg-Ab complexes formed are reversible
•Ucross linking of Ag-Ab complexes occurs forming lattices
•Uprecipitation or agglutination is visible
•UAg-Ab complexes formed are non-reversible and insoluble