Isoelectric
Focusing
General concept:
UBy creating a
pH gradient within the medium immunoglobulin molecules (amphoteric) will
move in an electrophoretic
system to a point where their isoelectric point is equal to the pH of medium
amphoteric
molecule = molecules that
can act as either a base or an acid depending on pH of medium in which they are suspended.
Clinical application:
U
identification of oligoclonal bands as in:
\multiple
sclerosis
\viral
encephalitis
\cerebral
infarction
\AIDS
