Waldenstrom=s - 3
Mechanism of Disease:
ecause unknown
egenetic predisposition may play a role
emainly seen in older individuals
epresents with the following features:
malignant proliferation of B cell line
increased plasma cell population
high levels of IgM produced
weakness, fatigue, nose & gum bleeds,
and GI bleeds
leads to anemia
increased infections
weight loss
increased blood viscosity
may develop neurological and cardiac problems
