Multiple
Sclerosis - 4
Laboratory Findings: continued
etwo assays used to determine origin of IgG
in CSF: cont=d
ŽCSF IgG index technique:
~this is a calculation that uses the ratio of
IgG to albumin in
both serum and CSF
CSF IgG index =
IgGCSF ) albuminCSF
IgGserum ) albuminserum
~interpretation of results:
q0.0 - 0.77
q> 0.77
serum IgG in CSF
IgG produced in CSF
