Factors
Affecting Agglutination - 1
U class of
antibody
U charge of
the Acarrier@ particles
U number of
epitopes
U concentration
of reactants
U environmental
factors
IgM better at
cross-linking due to size and number of paratopes than is IgG
many antigens
carry negative surface charges (zeta
potential) and this can be reduced by adding LISS thus allowing Ag=s to come closer together
antigens
containing multiple, densely distributed epitopes will cross-link more readily
