Factors Affecting Agglutination - 2
•
U
class of antibody
•
U
charge of the
A
carrier
@
particles
•
U
number of epitopes
•
U
concentration of reactants
•
U
environmental factors
•
generally the higher the concentrations the stronger
and faster the reaction
•
may get weak or negative reactions if
prozone (>Ab)
or
postzone
(>Ag)
exists
•
reactions enhanced by:
•
-proper mixing
•
-proper temperature
•
-proper incubation time
•
-proper centrifugation
•
-proper agitation
•
on previous screen