Ligase Chain Reaction (LCR)
&
Polymerase Chain Reaction (PCR)
&
Polymerase Chain Reaction (PCR)
Ligase chain reaction (LCR)
etarget sequence must be completely known vs PCR
where it is not known
eadvantage over PCR :
]able to
detect point mutations
Polymerase chain reaction (PCR)
eclinical applications of PCR:
]diagnosis of
sickle cell disease
]oncology
evaluation
]genetics
studies
]infectious
diseases (NAT)
]forensic
medicine (O.J. Simpson)
