General Features of ABO Antibodies
•In type A and type B individuals:
•What class of antibody:
•In type O individuals:
•Hemolytic properties:
•Both IgM and IgG anti-A and anti-B are capable of activating complement resulting in intravascular hemolysis of transfused red cells
•All anti-A and anti-B react at room temperature and require no further enhancement.
•Anti-A and Anti-B is primarily IgM with a little IgG
•Anti-A, Anti-B, and anti-A,B primarily IgG
•In vitro testing: