Weak
D (Du) antigen
•When the D antigen is not
detected using standard anti-D testing
procedures.
•Genetic – weak gene
expression (more common in Africans)
•Position effect – when C
antigen is in trans position to D
•Partial D – parts of the D
antigen are missing
•For all donor units –
labeled positive if weak D is detected
•When is it important to confirm a weak D:
•For all pregnant women – (OB
panel)