HbS Screening Test
Name of method:
Hemoglobin Solubility
Test
Principle of test:
When RBCs containing
HbS are mixed with a reducing substance such as sodium dithionite the HbS is insoluble and
precipitates causing increased turbidity
1. Blood is placed in a tube and
sodium dithionite
is added
Procedure of test:
2. The tube may then be centrifuge at
specific rcf
3. Tubes are then held up to a series
of lines for interpretation