Acute versus Chronic
Acute
Chronic
Onset
Abrupt
Feature
Insidious
Death
Age
WBC
Maturity (pb)
Maturity (bm)
Neutropenia
Anemia
Platelets
Organomegaly
Months
All
I/N/D
>20% blasts
>20% blasts
Present
Present (N/N)
Low
Mild
Years
Adults
Increased
<20% blasts
<20% blasts
Absent
Present (N/N)
N/I
Severe
Philadelphia chromosome