FAB Classification of ALL
Definitions:
L1:
FAB:
French-American-British
Smaller blasts
Flat, round or oval nuclei
Homogeneous chromatin
Nucleoli may not be visible
L2:
Large blasts
More irregular shaped nuclei
Nucleoli may be visible (>1)
L3:
Large blasts
Resembles malignant lymphocytes of Burkitt’s
lymphoma