Spleen - 4
Microenvironment of Spleen:
*   Red cells showing inclusion bodies have part of cell removed by macrophage
*   Macrophages phagocytize old red cells
*   Damaged or old red cells unable to maintain shape or integrity
*   Stagnant blood flow due to high number of cells
*   Depleted glucose by red cells
*   IgM synthesized in germinal centers