Cytokines - 3
Functions of specific cytokine:
Kit ligand
Colony-Stimulating factor (CSF)
o
highly specific
o
active at very low concentrations
o
named for target cells
o
activation of this receptor is essential for
early stages of hematopoiesis
o
proteins with multiple biologic activities
Interleukins (IL)
o
synergistic activities
o
amplification potential
o
effective at low concentrations