Facts about HMP
Function:
The
reducing of hydrogen peroxide and other oxidative compounds
to protect hemoglobin from being precipitated.
Most common
deficiency:
G-6-PD
most common deficiency
Hemoglobin
is denatured and forms precipitated bodies attached
to cell membrane
Results of
G-6-PD deficiency:
Heinz
bodies
On
Wright-Giemsa stain =
Name of
precipitated hemoglobin bodies:
Hematologic
evidence of Heinz bodies:
Bite
cells
On
Supravital stain =
Black,
round bodies