Cycle & Transport of Iron - 1
Principle protein regulators are:
transferrin
transferrin receptors
apoferritin
Facts related to transferrin:
Binds with Fe+++ in plasma and carries it to bone marrow
Plasma to erythroblast
Migrates in the b-globulin fraction on SPE
Binds to receptors on erythroblast membrane
Produced by hepatocytes
Transferrin binds to these
Binds iron to form ferritin – storage form