Physiologic Adaptations
Reduced
delivery of oxygen to tissue
Slowly
developing anemia
Requirements for adaptation to occur:
Process of
adaptation:
Kidneys
secrete erythropoietin
Increased
oxygen carrying capacity of hemoglobin
More
rapid delivery of blood to tissue
Increased
heart rate
Increased
respiratory rate
Increased
cardiac output
Increased
levels of RBC 2-3,BPG
Decreased
oxygen-affinity
Shift-to-right
of oxygen dissociation curve