General Concepts of Anemia
Factors leading to anemias:
1. Impaired production of
erythrocytes
a. Lack of iron:
IDA
Inadequate stores of iron
Impaired mobilization of
iron
AOCD
b. Lack of heme:
Intrinsic defect in iron
insertion
SA
c. Lack of globin:
Decreased production of
globin
Thalassemia
2. Shortened survival time of
erythrocytes
3. Loss of erythrocytes
SA =
sideroblastic anemia
IDA
= iron deficiency anemia
AOCD
= anemia of chronic disease