Iron Deficiency Anemia
Etiology of anemia:
1. Inadequate iron intake
2. Increased demand for iron
3. Chronic blood loss
Pathogenesis of anemia:
Three
compartments of iron:
Storage:
Ferritin in bm macrophages
& liver
Transport:
Serum transferritin (serum
ferritin)
Functional:
Hb, myoglobin, &
cytochromes
NOTE: 95% of body iron
is as hemoglobin or serum ferritin