CDA types - 1
Anemia
=
Acid
serum test =
Macrocytic normochromic
negative
CDA
type 1
Clinical features:
CDA
type 2 – (also called HEMPAS cells) most common
Sugar
water test =
negative
Anemia
=
Acid
serum test =
Sugar
water test =
Normocytic normochromic
positive
negative
CD55
& CD59 =
Cells
of PNH positive for both acid serum & sugar water tests
normal levels
HEMPAS = hereditary erythroblastic multinuclearity with positive acid serum test
Cells
of PNH have decreased levels of CD55 & CD59
Acid
serum test also called Ham’s test