Unit Objectives - 5

Unit objectives:

24. Describe the hemolytic anemia and nocturnal hemoglobinuria that may be associated with PNH.

23. Classify the subpopulations of PNH erythrocytes according to their deficiency of immunologically attached surface proteins as measured by flow cytometry.

22. Explain the main defect in paroxysmal nocturnal hemoglobinuria (PNH).

21. Define porphyrias and explain the basic mechanism for the hereditary diseases.