Stomatocytic HE Features
Incidence:
Southeast
Asia – Melanesian & Malaysian
RBC morphology
Appear
as double stomatocytes
Clinical features:
Mild
or absent hemolysis
Lab findings:
Normal
osmotic fragility
Heat
resistant – maintain integrity to 52oC
Alternate name:
Southeast
Asia Ovalocytosis (SAO)
Cells
resistant to malaria parasite invasion