Acanthocytosis Features
Defect:
Normal
protein concentration in membrane
Decreased
phosphatidylcholine – increased sphingomyelin
Abetalipoproteinemia
Lab features:
Acanthocyte
formation in older red cells
Normal
osmotic fragility
Chylomicron
retention disease
Inheritance:
Normal
MCHC, MCH, and MCV
Rare
autosomal recessive