Acanthocytosis & Diseases - 1
Deseases presenting with acanthocytosis:
Abetalipoproteinemia:
Steatorrhea
in 1st month of life
Absence
of LDL
Patient
dies by age of 20 – 30 years
Mild
anemia
Lipoprotein
defects:
hypobetalipoproteinemia
Chylomicron
retention disease
Neurological
abnormalities based on severity of lipoprotein deficiency
In(Lu)
gene
Inhibitor
of Lutheran (Lua and Lub)
antigens
Normal
to mild hemolytic anemia