G6PD Deficiency Features - 1
Defect:
Mutant
gene on X-chromosome
Inheritance:
Classes of genetic expression:
Sex-linked
co-dominant
Class
I:
Class
II:
Class
III:
Class
IV:
Class
V:
Severe
clinical symptoms - <20% activity
Mild
clinical symptoms - <10% activity
Mild
clinical symptoms – 10-60% activity
No
clinical symptoms – 100% activity
No
clinical symptoms - >100% activity
Activity = level of G6PD
produced
Most common expression =
class I
