G6PD Deficiency Features - 3
G6PD variants:
Mahidol
variant
G6PD-mah
G6PD-can
Thailand
& Vietnam
Canton
variant
Chinese
and Southeast Asians
Meaning of
G6PD :
Glucose-6-phosphate
Dehydrogenase
Function of
G6PD :
Reduces
nicotinamide-adenine dinucleotide phosphate (NADP)
to NADPH while oxidizing glucose-6-phosphate
Function of
NADP :
Reduced
NADPH transfers it’s H+ (by action of glutathione
reductase) to restore reduced glutathione (GSH)