PNH - 1
Inheritance:
Somatic
mutation of gene on X chromosome
Incidence:
Defects:
Individuals
having previous:
Aplastic
anemia – 30% of PNH cases
Pancytopenia
The above may be as a
result of drugs or idiopathic
Cells
affected include:
granulocytes
platelets
red
blood cells
lymphocytes