Warm-Reactive AIHA - 2
Antibody types associates with warm-reactive
AIHA:
IgG1
74%
Very
rare – monoclonal type
20.1% IgG1 plus other
subclass
IgG2
IgG3
IgG4
IgM
2.1%
3.8% IgG3 and IgG4 subclasses
Antibody types
associated with complement activation:
All
subclasses of IgG can activate complement
IgG1 and IgG3 do it
best
Type of
hemolysis:
Extravascular