Secondary Cold-Reactive AIHA - 2
Screening tests:
Submerge
anticoagulated blood specimen in ice bath:
No
Agglutination occurs:
Agglutination
occurs:
Tube placed in 37oC
Positive for cold AIHA if agglutination disappears
DAT:
Positive
at 15 – 32oC
only for complement (C3d/C3b)
Treatment:
Avoid
exposing extremities to cold