PCH - 2
Inducing disorders:
Congenital
or tertiary syphilis
Viral
infections
DAT:
Why?
Negative
for IgG but positive for C3d/C3b
Type
of anemia:
Lab features:
Donath-Landsteiner
antibodies are dissociated from RBCs at warm temperatures
chronic
Retic
count:
increased
Hb:
decreased
Haptoglobin:
decreased
bilirubin:
increased
hemoglobinemia:
positive
Blood
film:
Spherocytes
& phagocytized RBCs