Drug-Induced HA - 4
Types of Drug-Induced HA:
Autoantibody type:
Drug induces production of autoantibodies
directed against RBC antigens
Intravascular and/or Extravascular hemolysis
Drugsinvolved:
aldomet (
a
-methyldopa)
procainamide
DAT:
AIHA resolved with removal of drug
Positive for up to 2 years