Unit Objectives - 1

Reading assignment:

Pages 319 - 337

Unit objectives:

1. Characterize the categories of the molecular abnormalities found in the various hemoglobinopathies.

2. Differentiate between homozygous and heterozygous states, and qualitative and quantitative hemoglobin defects.

3. Define the pathologic basis of sickle cell disorder.

4. Describe the inheritance pattern of hemoglobin S variant.