Unit Objectives - 2

Unit objectives:

5. State the amino acid substitution found in hemoglobin S.

6. Describe the solubility of HbS due to deoxygenation.

7. Differentiate among the types of sickle cell crises.

8. Locate the geographic region, define the frequency of occurrence, and describe the impact of the incidence of Plasmodium falciparum and G6PD deficiency on hemoglobin variants.

9. Describe the peripheral blood cell profile, chemistries, and other lab procedures used in the diagnosis of hemoglobinopathies.