CLSC411

Hemoglobinopathies - 2

States of hemoglobin in beta chain abnormalities:

HOMOZYGOUS

HETEROZYGOUS

Conc. Of variant

Highest

Lower or + to Hb A

Hb A

Absent

Present

Examples

Hb SS

Hb C, Hb S

States of hemoglobin in alpha chain abnormalities:

Hemoglobins affected:

Hb A, Hb F, and Hb A2 since all have alpha chains

Hb Gower 2 since it has alpha chains