Hemoglobin S - Incidence
Most common hemoglobinopathy
12%
African-Americans with a Hb S variant
20-40%
carriers in Africa
0.3%
African-American births have Hb SS
8-10%
African-Americans have Hb S trait
Other races Hb
S more common in:
Middle
Eastern
Indian
Mediterranean
Caribbean
Central
and South American
Double
homozygous state::
Hb
SC = 0.12% of African-Americans
Hb
S/b-thal = 0.16% of African-Americans