Hb S – Clinical Features - 4
Megaloblastic crises:
Features:
Sudden
stop of erythropoiesis
Due
to folate deficiency
Folate
Therapy:
Sequestration
crises:
Features:
Sudden
trapping of RBCs by spleen
Rapid
drop in Hb (<6 g/dL)
Most
common in infants and young adults
Therapy:
Splenectomy