Unit Objectives - 1
Reading assignment:
Pages 339 - 358
Unit objectives:
1. Describe the hemoglobin defect found in thalassemias.
2. Name the chromosomes that contain the alpha gene and the beta gene clusters and the globin
chains
produced by each.
3. Explain the geographic distribution of thalassemia and its association
with malaria.
4. Explain the pathophysiology caused by the imbalance of the globin
chain synthesis
in thalassemia.