Lab Testing in Thalassemia - 1
Osmotic fragility test:
Decreased
as it is in IDA
Brilliant
cresyl blue:
Uniformly
positive for Hb H
Precipitate
gives a “golf ball” or “raspberry” appearance
In a-thalassemia
only few RBCs positive
Special
stains:
Hemoglobin
electrophoresis:
Hemoglobin A2 by column
chromatography:
