Pelger-Hüet Anomaly
Incidence:
A
common inherited disorder.
Of clinical
significance?
Yes
Features:
Less
dense nuclei
Hypogranular
cytoplasm
Etiology:
High
stress situations such as:
Burns,
drug reactions, infections
Myelodysplastic
syndrome
Chronic
granulocytic leukemia (CGL)
Acute
leukemias