What does it
do?
Results
in the formation of large granules
Abnormality:
Uncontrolled
activity of granular membrane
Peroxidase-positive
blue-gray granules
Appearance:
Disorders:
Increased
susceptibility to infections
All
cells have shortened life span and are ineffective
Chédiak-Steinbrinck-Higashi Syndrome
Cells
affected:
Increased
bleeding time
Decreased
clotting retraction
Prognosis:
Death
as a result of lymphadenopathy and hepatomegaly