Granulocytes and monocytes/macrophages
Abnormality:
Chronic Granulomatous-1
Cells affected:
Collection of geneic disorders
Disorder:
Respiratory burst
Intracellular killing mechanism of granulocytes and monocytes/macrophages is defective due to absence/deficiency/or defect in:
Membrane nicotinamide-adenine dinucleotide (NADH)
Reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase
Reduced cytosolic factor
Cytochrome B