Monoclonal Antibody Production
Monoclonal antibodies:
Antigens
are injected into an animal such as:
When
an immune response is achieved the B cells are harvested
from:
mouse
spleen
Lymph
nodes
The
B cells secreting antibodies of desired specificity are then
fused with myeloma cells to form hybridoma cells
The hybridoma cells are
then cloned and all offspring produce identical antibodies
with desired specificity.