Structural Abnormalities - I
Caused by:
Breakage
of a region with subsequent loss or rejoining in
an abnormal combination
Inversions:
Types of
abnormalities:
One or two breaks
occurs:
Pericentric
if centromeres involved
paracentric
if centromeres not involved
Deletions:
Two breaks occurs with
loss of material between breaks
Isochromosomes:
When abnormal division
of centromeres takes place